May 21, 2016
Dr. Pouya Khankhanian describes his experience with "worst headache of life." A harbinger of head pathology, thunderclap headache should be quickly and meticulously addressed in order to prevent life-threatening neurologic disease. BrainWaves podcasts and online content are intended for medical education only and should not be used to guide medical decision making in routine clinical practice. Any cases discussed in this episode are fictional and do not contain any patient health identifying information. The content in this episode was vetted and approved by Roderick Spears. REFERENCES 1. Schwedt TJ, Matharu MS and Dodick DW. Thunderclap headache. The Lancet Neurology. 2006;5:621-31. 2. Linn FH, Wijdicks EF, van der Graaf Y, Weerdesteyn-van Vliet FA, Bartelds AI and van Gijn J. Prospective study of sentinel headache in aneurysmal subarachnoid haemorrhage. Lancet. 1994;344:590-3. 3. Sames TA, Storrow AB, Finkelstein JA and Magoon MR. Sensitivity of new-generation computed tomography in subarachnoid hemorrhage. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine. 1996;3:16-20. 4. van der Wee N, Rinkel GJ, Hasan D and van Gijn J. Detection of subarachnoid haemorrhage on early CT: is lumbar puncture still needed after a negative scan? Journal of neurology, neurosurgery, and psychiatry. 1995;58:357-9. 5. Vergouwen MD and Rinkel GJ. Clinical suspicion of subarachnoid hemorrhage and negative head computed tomographic scan performed within 6 hours of headache onset--no need for lumbar puncture. Ann Emerg Med. 2013;61:503-4. 6. Edlow JA and Caplan LR. Avoiding pitfalls in the diagnosis of subarachnoid hemorrhage. The New England journal of medicine. 2000;342:29-36. 7. Vermeulen M, Hasan D, Blijenberg BG, Hijdra A and van Gijn J. Xanthochromia after subarachnoid haemorrhage needs no revisitation. Journal of neurology, neurosurgery, and psychiatry. 1989;52:826-8. 8. Muehlschlegel S, Kursun O, Topcuoglu MA, Fok J and Singhal AB. Differentiating reversible cerebral vasoconstriction syndrome with subarachnoid hemorrhage from other causes of subarachnoid hemorrhage. JAMA Neurol. 2013;70:1254-60. 9. Misra UK, Kalita J, Chandra S, Kumar B and Bansal V. Low molecular weight heparin versus unfractionated heparin in cerebral venous sinus thrombosis: a randomized controlled trial. European journal of neurology : the official journal of the European Federation of Neurological Societies. 2012;19:1030-6.