Aug 16, 2018
Lesion localization is a critical skill for any neurologist. The
so-called "cortical signs" are symptoms or exam findings which are
often associated with cortical neuron injury--aphasia, neglect,
gaze preference. But they are also seen after injury to subcortical
structures, including white matter tracts, the thalamus, and basal
ganglia. In this week's installment of the BrainWaves podcast,
we'll attempt to localize subcortical lesions based on these major
Produced by James E. Siegler. Music by Aussenseiter, Gnagno,
Yshwa, and Kevin McLeod. BrainWaves' podcasts and online content
are intended for medical education only and should not be used for
clinical decision making.
- Maeshima S and Osawa A. Thalamic Lesions and Aphasia or
Neglect. Current neurology and neuroscience reports.
- Bogousslavsky J, Regli F and Uske A. Thalamic infarcts:
clinical syndromes, etiology, and prognosis. Neurology.
- Karnath HO, Himmelbach M and Rorden C. The subcortical anatomy
of human spatial neglect: putamen, caudate nucleus and pulvinar.
- Lam YW and Sherman SM. Functional organization of the thalamic
input to the thalamic reticular nucleus. J Neurosci.
- Tijssen CC. Contralateral conjugate eye deviation in acute
supratentorial lesions. Stroke; a journal of cerebral
- Fridriksson J, den Ouden DB, Hillis AE, Hickok G, Rorden C,
Basilakos A, Yourganov G and Bonilha L. Anatomy of aphasia
revisited. Brain. 2018. Epub ahead of print.
- Nadeau SE and Crosson B. Subcortical aphasia. Brain
Lang. 1997;58:355-402; discussion 418-23.